Novak Djokovic reached the Wimbledon quarter-finals for the 16th time but it proved a hard day's work at his Centre Court office.
The Swiss three-time grand slam champion was out-gunned by 21-year-old Medvedev, who had the Centre Court crowd on their feet as he pulled off a dazzling array of winners to wrap up a 6-4, 3-6, 6-4, 6-1 victory on his first Wimbledon appearance.
Under the lights on the stadium court, Williams smashed 39 winners to defeat Azarenka 7-5, 6-3 in a rematch of the 2016 final, which the Belarusian won.
'Yes, I fall over, but grass sometimes is slippery. Nothing happens. I am good, yeah. Nothing'
In the first women's final played under the Centre Court roof, a high-quality first set gradually built towards a captivating conclusion after both players began with two comfortable service holds.
15-year-old Cori Gauff, the youngest at this year's Wimbledon will play her opening round match against the oldest player at the Championships - Venus Williams. The duel is billed as 'clash of the generations'.
This is not the first time that Murray has won our hearts with his stance against sexism.
The Serbian top seed won a fourth successive title at the All England Club to take his overall Grand Slam tally to 21.
Images from the Wimbledon semi-final played between Roger Federer and Rafael Nadal on Friday
IMAGES from Day 7 of the Wimbledon Championships, at the All England Lawn Tennis and Croquet Club, London, on Sunday.
Murray was slightly vexed by a question at the post-match news conference that suggested the fans' loyalties were more divided than if he were playing anyone but Federer.
IMAGES from Day 6 of the Wimbledon Championships, at the All England Lawn Tennis and Croquet Club, London, on Saturday.
IMAGES from Day 4 of the Wimbledon Championships, at the All England Lawn Tennis and Croquet Club, London, on Thursday.
Top seed Novak Djokovic set up a blockbuster Wimbledon final against Nick Kyrgios after recovering from a torrid start to overwhelm Britain's Cameron Norrie 2-6, 6-3, 6-2, 6-4 on Friday.
'I'm a professional competitor who did her best today, and that's all there is to that'
Riske created one of the biggest shocks of the tournament with her 3-6, 6-2, 6-3 victory over French Open champion Barty who was on the sort of run that made losing to a player of the American's lowly 55th ranking appear almost impossible.
IMAGES from the matches played on Day 3 of the Wimbledon Lawn Tennis Championships at All England Lawn Tennis and Croquet Club on Wednesday
A year after Andy Murray's reign as Wimbledon champion ended lamely at the hands of a man dubbed the new Roger Federer, he got a stark reminder on Friday that the original is the real threat to his grand slam ambitions.
Friday's showdown will be the 40th meeting between the duo with Rafael Nadal leading 24-15 and 10-3 in Grand Slams.
The 23-year-old Kazakh, whose previous best performance in a Grand Slam was reaching the quarter-final at the French Open last year, would like TO create history on the hallowed turf of the All England Lawn Tennis and Croquet Club.
IMAGES from Day 1 of the Wimbledon Championships, at the All England Lawn Tennis and Croquet Club, London, on Monday.
A summary of Novak Djokovic's rise in the tennis circuit in photos.
The big-serving seventh seed, who has flown somewhat under the radar throughout the Championships, will meet the winner of the second semi-final between Serbia's Novak Djokovic and Canadia's Denis Shapovalov in Sunday's final.
IMAGES from Day 6 of the Wimbledon Championships, at the All England Lawn Tennis and Croquet Club, London, on Saturday.
Images from Day 9 of the Wimbledon 2022 Championships at the All England Lawn Tennis and Croquet Club in London, on Tuesday.
Since Andy Murray's memory is as razor sharp as his service returns, he will not have forgotten the parting shot he received from Milos Raonic when they last played.
Images from the first Wimbledon semi-final between Serbia's Novak Djokovic and Spain's Roberto Batista Agut at the All England Lawn Tennis and Croquet Club on Friday
Images from Day 8 of Wimbledon 2024 at The All England Lawn Tennis and Croquet Club in London on Monday.
PHOTOS from day two of the Wimbledon championships at the All England Lawn Tennis and Croquet Club in London on Tuesday.
Croatian Cilic, who lost last year's final to Roger Federer, underlined his credentials for another Grand Slam title bid to add to his U.S. Open triumph in 2014.
IMAGES from Day 10 of the Wimbledon 2022 Championships at the All England Lawn Tennis and Croquet Club in London, on Wednesday.
Images from Day 8 of Wimbledon 2022 at the All England Lawn Tennis and Croquet Club in London, on Monday.
PHOTOS from day three of the Wimbledon championships at the All England Lawn Tennis and Croquet Club in London on Wednesday.
IMAGES from the matches played on Day 2 of the Wimbledon Lawn Tennis Championships at All England Lawn Tennis and Croquet Club on Tuesday.
Images from Day 9 of Wimbledon at the All England Lawn Tennis and Croquet Club in London, on Wednesday.
Images from the 2022 Wimbledon Championships at the All England Club in London on Sunday.
'I mean, that was one thing that I promised myself coming on to the court today, that I need to stay calm and composed, because I knew that the atmosphere would be as it was'
PHOTOS from day seven of the Wimbledon championships at the All England Lawn Tennis and Croquet Club in London on Monday
IMAGES from the matches played on Day 4 of the Wimbledon Lawn Tennis Championships at All England Lawn Tennis and Croquet Club on Thursday
IMAGES from Day 2 of the Wimbledon Championships from the All England Lawn Tennis and Croquet Club, London, on Tuesday.